PRMT5-MTA-IN-4, CAS [[3025838-18-7]] Preis auf Anfrage

Product Overview

• Article Name: PRMT5-MTA-IN-4, CAS [[3025838-18-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-176701
• Supplier Catalog Number: HY-176701
• Alternative Catalog Number: MCE-HY-176701-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PRMT5-MTA-IN-4 (Compound 30) is a potent irreversible protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50=8 nM). PRMT5-MTA-IN-4 blocks arginine methylation, inhibiting ribosomal RNA processing and cell cycle-related protein expression. PRMT5-MTA-IN-4 exhibits antiproliferative activity in multiple tumor cell lines (e.g., IC50=0.3 µM in DLD-1 cells). PRMT5-MTA-IN-4 is promising for research of hematological malignancies, such as acute myeloid leukemia, diffuse large B-cell lymphoma[1].

Product Properties

• Molecular Weight: 504.94
• CAS Number: [3025838-18-7]
• Formula: C26H22ClFN6O2
• Target: Histone Methyltransferase

Application Notes

• Application Notes: MCE Product type: Reference compound