PROTAC HER2 degrader-1, CAS [[2897640-93-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC HER2 degrader-1, CAS [[2897640-93-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-177008
• Hersteller Artikelnummer: HY-177008
• Alternativnummer: MCE-HY-177008-5MG,MCE-HY-177008-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC HER2 degrader-1 is a highly selective HER2 PROTAC degrader, with a DC50 of 69 nM and a Dmax of 96%. PROTAC HER2 degrader-1 inhibits HER2-positive cell proliferation and tumor growth through persistent HER2 degradation and potent inhibition of downstream pathways (AKT and ERK). PROTAC HER2 degrader-1 induces apoptosis in BT-474 cells. PROTAC HER2 degrader-1 can be used for research of HER2-positive cancers. (Pink: HER2 ligand: (HY-177009), Black: Linker, Blue: CRBN ligand: (HY-W023573)[1].

Produkteigenschaften

• Molekulargewicht: 910.03
• Reinheit: 98
• CAS Nummer: [2897640-93-4]
• Formel: C49H55N11O7
• Target-Kategorie: Akt,Apoptosis,EGFR,ERK,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound