PROTAC HER2 degrader-1, CAS [[2897640-93-4]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC HER2 degrader-1, CAS [[2897640-93-4]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-177008
• Supplier Catalog Number: HY-177008
• Alternative Catalog Number: MCE-HY-177008-5MG,MCE-HY-177008-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC HER2 degrader-1 is a highly selective HER2 PROTAC degrader, with a DC50 of 69 nM and a Dmax of 96%. PROTAC HER2 degrader-1 inhibits HER2-positive cell proliferation and tumor growth through persistent HER2 degradation and potent inhibition of downstream pathways (AKT and ERK). PROTAC HER2 degrader-1 induces apoptosis in BT-474 cells. PROTAC HER2 degrader-1 can be used for research of HER2-positive cancers. (Pink: HER2 ligand: (HY-177009), Black: Linker, Blue: CRBN ligand: (HY-W023573)[1].

Product Properties

• Molecular Weight: 910.03
• Purity: 98
• CAS Number: [2897640-93-4]
• Formula: C49H55N11O7
• Target: Akt,Apoptosis,EGFR,ERK,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound