IL-6-IN-2 (Compound 15) is an inhibitor of the IL-6/IL-6R protein interaction. The deltaG binding energy of IL-6-IN-2 is -36.50 kcal/mol. Contributions of Lys66, Phe74, Gln175, Ser176, and Arg179 to IL-6 binding are -1.10, -8.68, -6.91, -3.69, and -1.72 kcal/mol, respectively. IL-6-IN-2 exhibits low gastrointestinal (GI) absorption[1].
Molekulargewicht:
440.49
Reinheit:
99.95
CAS Nummer:
[296790-70-0]
Formel:
C26H24N4O3
Target-Kategorie:
Interleukin Related
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
