IL-6-IN-2 is an interleukin-6 (IL-6) inhibitor. IL-6-IN-2 binds to IL-6 at Lys66, Phe74, Gln175, Ser176, and Arg179 via pi-pi, pi-alkyl, hydrogen bond, and hydrophobic interactions to block IL-6/IL-6R heterocomplex formation. IL-6-IN-2 exhibits low gastrointestinal absorption rate. IL-6-IN-2 can be used for the research of cytokine release syndrome, covid-19[1].
Molekulargewicht:
440.49
Reinheit:
99.95
CAS Nummer:
[296790-70-0]
Formel:
C26H24N4O3
Target-Kategorie:
Interleukin Related
Anwendungsbeschreibung:
MCE Product type: Reference compound
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