IL-6-IN-2 (Compound 15) is an inhibitor of the IL-6/IL-6R protein interaction. The deltaG binding energy of IL-6-IN-2 is -36.50 kcal/mol. Contributions of Lys66, Phe74, Gln175, Ser176, and Arg179 to IL-6 binding are -1.10, -8.68, -6.91, -3.69, and -1.72 kcal/mol, respectively. IL-6-IN-2 exhibits low gastrointestinal (GI) absorption[1].
Molecular Weight:
440.49
Purity:
99.95
CAS Number:
[296790-70-0]
Formula:
C26H24N4O3
Target:
Interleukin Related
Application Notes:
MCE Product type: Reference compound
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