SV119 (hydrochloride), CAS [[913816-12-3]] Preis auf Anfrage

Artikelnummer: MCE-HY-177345A
Artikelname: SV119 (hydrochloride), CAS [[913816-12-3]] Preis auf Anfrage
Artikelnummer: MCE-HY-177345A
Hersteller Artikelnummer: HY-177345A
Alternativnummer: MCE-HY-177345A-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
SV119 hydrochloride is a sigma-2 ligand with a Ki value of 5.2 nM. SV119 hydrochloride enhances the efficient transport of drugs across the plasma membrane of cancer cells. The conjugation of dm-Erastin with SV119 hydrochloride successfully overcomes the internalization barrier observed in pancreatic cancer, while preserving the inherent anti-tumor activity of Erastin (HY-15763). Additionally, SV119 hydrochloride demonstrates cytotoxic effects on triple-negative breast cancer (TNBC) cells and induces apoptosis[1][2].
Molekulargewicht: 476.48
CAS Nummer: [913816-12-3]
Formel: C23H39Cl2N3O3
Target-Kategorie: Apoptosis,Sigma Receptor
Anwendungsbeschreibung: MCE Product type: Reference compound