SV119 (hydrochloride), CAS [[913816-12-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-177345A
Supplier Catalog Number:
HY-177345A
Alternative Catalog Number:
MCE-HY-177345A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
SV119 hydrochloride is a sigma-2 ligand with a Ki value of 5.2 nM. SV119 hydrochloride enhances the efficient transport of drugs across the plasma membrane of cancer cells. The conjugation of dm-Erastin with SV119 hydrochloride successfully overcomes the internalization barrier observed in pancreatic cancer, while preserving the inherent anti-tumor activity of Erastin (HY-15763). Additionally, SV119 hydrochloride demonstrates cytotoxic effects on triple-negative breast cancer (TNBC) cells and induces apoptosis[1][2].
Molecular Weight:
476.48
CAS Number:
[913816-12-3]
Formula:
C23H39Cl2N3O3
Target:
Apoptosis,Sigma Receptor
Application Notes:
MCE Product type: Reference compound
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