VR11 aptamer is a DNA-based TNF-alpha inhibitor with a KD of 7.0 nM. VR11 aptamer prevents TNFalpha-induced apoptosis and NO production. VR11 aptamer has non-immunogenicity and does not raise immune responses when injected intraperitoneally into C57BL/6 mice model. VR11 aptamer can be used for inflammatory diseases research[1].
Target-Kategorie:
Apoptosis,NO Synthase,TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Oligonucleotides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
