h-FTAA is a luminescent conjugated oligothiophene (LCO) probe. h-FTAA can selectively bind to amyloid protein aggregates (such as Abeta plaques) and distinguish different conformations of the protein aggregates through changes in fluorescence signals. h-FTAA significantly reduces the neurotoxicity of Abeta1-42 and the Arctic mutant Abeta (AbetaArc), thereby protecting SH-SY5Y neuroblastoma cells. h-FTAA can be used to dynamically track the formation and maturation process of Abeta plaques[1][2].
Molekulargewicht:
780.97
CAS Nummer:
[1352477-26-9]
Formel:
C34H20O8S7
Target-Kategorie:
Amyloid-beta,Fluorescent Dye
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
