h-FTAA is a luminescent conjugated oligothiophene (LCO) probe. h-FTAA can selectively bind to amyloid protein aggregates (such as Abeta plaques) and distinguish different conformations of the protein aggregates through changes in fluorescence signals. h-FTAA significantly reduces the neurotoxicity of Abeta1-42 and the Arctic mutant Abeta (AbetaArc), thereby protecting SH-SY5Y neuroblastoma cells. h-FTAA can be used to dynamically track the formation and maturation process of Abeta plaques[1][2].
Molecular Weight:
780.97
CAS Number:
[1352477-26-9]
Formula:
C34H20O8S7
Target:
Amyloid-beta,Fluorescent Dye
Application Notes:
MCE Product type: Reference compound
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