MS99-beta-Gal, CAS [[3055593-63-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: MS99-beta-Gal, CAS [[3055593-63-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-177945
• Hersteller Artikelnummer: HY-177945
• Alternativnummer: MCE-HY-177945-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: Gal-MS99

Produktbeschreibung

MS99-beta-Gal (Gal-MS99) is a galactose-modified NPM-ALK PROTAC degrader. MS99-beta-Gal is only hydrolyzed by SA-beta-gal and esterase in senescent cancer cells, releasing MS99, which specifically degrades the NPM-ALK fusion protein. MS99-beta-Gal shows an IC50 of 454.8 nM for aging Karpas 299 cells, significantly lower than that of normal Karpas 299 cells (IC50 = 2.162 µM). MS99-beta-Gal can be used for the research of cancer[1].

Produkteigenschaften

• Molekulargewicht: 1579.23
• CAS Nummer: [3055593-63-7]
• Formel: C78H96ClN9O20S2
• Target-Kategorie: Anaplastic lymphoma kinase (ALK),PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound