MS99-beta-Gal, CAS [[3055593-63-7]] Preis auf Anfrage

Product Overview

• Article Name: MS99-beta-Gal, CAS [[3055593-63-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-177945
• Supplier Catalog Number: HY-177945
• Alternative Catalog Number: MCE-HY-177945-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: Gal-MS99

Product Description

MS99-beta-Gal (Gal-MS99) is a galactose-modified NPM-ALK PROTAC degrader. MS99-beta-Gal is only hydrolyzed by SA-beta-gal and esterase in senescent cancer cells, releasing MS99, which specifically degrades the NPM-ALK fusion protein. MS99-beta-Gal shows an IC50 of 454.8 nM for aging Karpas 299 cells, significantly lower than that of normal Karpas 299 cells (IC50 = 2.162 µM). MS99-beta-Gal can be used for the research of cancer[1].

Product Properties

• Molecular Weight: 1579.23
• CAS Number: [3055593-63-7]
• Formula: C78H96ClN9O20S2
• Target: Anaplastic lymphoma kinase (ALK),PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound