H3R antagonist 8, CAS [[3097193-89-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: H3R antagonist 8, CAS [[3097193-89-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-178016
• Hersteller Artikelnummer: HY-178016
• Alternativnummer: MCE-HY-178016-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

H3R antagonist 8 is a selective nonimidazole histamine H3 receptor antagonist (IC50 = 0.35 µM). H3R antagonist 8 exhibits hERG channel blockade activity (IC50 = 0.67 µM). H3R antagonist 8 inhibits seizures by antagonizing H3 receptor. H3R antagonist 8 reduces tonic hind limb extension (THLE) in mice in the maximal electroshock seizure (MES) model (ED50 = 20.21 mg/kg) and and shortens pentylenetetrazol (PTZ)-induced total movement distance in AB strain zebrafish larvae. H3R antagonist 8 can be used for the study of epilepsy[1].

Produkteigenschaften

• Molekulargewicht: 398.93
• CAS Nummer: [3097193-89-7]
• Formel: C23H27ClN2O2
• Target-Kategorie: Histamine Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound