H3R antagonist 8, CAS [[3097193-89-7]] Preis auf Anfrage

Product Overview

• Article Name: H3R antagonist 8, CAS [[3097193-89-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-178016
• Supplier Catalog Number: HY-178016
• Alternative Catalog Number: MCE-HY-178016-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

H3R antagonist 8 is a selective nonimidazole histamine H3 receptor antagonist (IC50 = 0.35 µM). H3R antagonist 8 exhibits hERG channel blockade activity (IC50 = 0.67 µM). H3R antagonist 8 inhibits seizures by antagonizing H3 receptor. H3R antagonist 8 reduces tonic hind limb extension (THLE) in mice in the maximal electroshock seizure (MES) model (ED50 = 20.21 mg/kg) and and shortens pentylenetetrazol (PTZ)-induced total movement distance in AB strain zebrafish larvae. H3R antagonist 8 can be used for the study of epilepsy[1].

Product Properties

• Molecular Weight: 398.93
• CAS Number: [3097193-89-7]
• Formula: C23H27ClN2O2
• Target: Histamine Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound