AHR agonist 10, CAS [[1191937-43-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: AHR agonist 10, CAS [[1191937-43-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-178053
• Hersteller Artikelnummer: HY-178053
• Alternativnummer: MCE-HY-178053-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

AHR agonist 10 is a potent AHR agonist (EC50 = 2.01 nM). AHR agonist 10 can elevate the transcript levels of key AHR downstream pathway target genes, including CYP1A1 and CYP1B1. AHR agonist 10 can downregulate the expression levels of CD36, IL-18 and shows low cytotoxicity (>40 µM) to normal cells. AHR agonist 10 can suppress the expression of CCL5, CCL20, IL-6, IL-8, S100A9, TLR4, TNF-alpha, and TNFR1, demonstrating that AHR agonist 10 effectively modulate inflammatory responses through AHR dependent signaling pathways. AHR agonist 10 can be used for psoriasis research[1].

Produkteigenschaften

• Molekulargewicht: 284.35
• CAS Nummer: [1191937-43-5]
• Formel: C18H20O3
• Target-Kategorie: Aryl Hydrocarbon Receptor,Cytochrome P450,Interleukin Related

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound