AHR agonist 10, CAS [[1191937-43-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-178053
Supplier Catalog Number:
HY-178053
Alternative Catalog Number:
MCE-HY-178053-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
AHR agonist 10 is a potent AHR agonist (EC50 = 2.01 nM). AHR agonist 10 can elevate the transcript levels of key AHR downstream pathway target genes, including CYP1A1 and CYP1B1. AHR agonist 10 can downregulate the expression levels of CD36, IL-18 and shows low cytotoxicity (>40 µM) to normal cells. AHR agonist 10 can suppress the expression of CCL5, CCL20, IL-6, IL-8, S100A9, TLR4, TNF-alpha, and TNFR1, demonstrating that AHR agonist 10 effectively modulate inflammatory responses through AHR dependent signaling pathways. AHR agonist 10 can be used for psoriasis research[1].
Molecular Weight:
284.35
CAS Number:
[1191937-43-5]
Formula:
C18H20O3
Target:
Aryl Hydrocarbon Receptor,Cytochrome P450,Interleukin Related
Application Notes:
MCE Product type: Reference compound
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