DNA polymerase-IN-7 is a noncompetitive inhibition of DNA Polymerase beta with an IC50 of 112 nM and a Ki of 35 nM. DNA polymerase-IN-7 can inhibit DNA pol beta lyase activity and the binding of the lyase domain of Pol beta to DNA. DNA polymerase-IN-7 can be used for the research of cancer, such as cervical cancer[1].
Molekulargewicht:
901.90
Formel:
C47H48N7O10P
Target-Kategorie:
DNA/RNA Synthesis
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
