DNA polymerase-IN-7 is a noncompetitive inhibition of DNA Polymerase beta with an IC50 of 112 nM and a Ki of 35 nM. DNA polymerase-IN-7 can inhibit DNA pol beta lyase activity and the binding of the lyase domain of Pol beta to DNA. DNA polymerase-IN-7 can be used for the research of cancer, such as cervical cancer[1].
Molecular Weight:
901.90
Formula:
C47H48N7O10P
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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