AR antagonist 17, CAS [[3064715-04-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: AR antagonist 17, CAS [[3064715-04-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-178148
• Hersteller Artikelnummer: HY-178148
• Alternativnummer: MCE-HY-178148-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

AR antagonist 17 is a selective, orally active, low brain-penetrant Androgen Receptor (AR) antagonist (IC50 = 0.010 µM), effectively blocking AR dimerization and nuclear translocation, and demonstrating potent efficacy in several castration-resistant prostate cancer (CRPC) cells. AR antagonist 17 showed superior efficacy against variant drug-resistant AR mutants. AR antagonist 17 can inhibit tumor growth in an LNCaP xenograft model without apparent toxicity. AR antagonist 17 can be used for the study of castration-resistant prostate cancer (CRPC)[1].

Produkteigenschaften

• Molekulargewicht: 499.53
• CAS Nummer: [3064715-04-1]
• Formel: C21H20F3N3O4S2
• Target-Kategorie: Androgen Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound