AR antagonist 17, CAS [[3064715-04-1]] Preis auf Anfrage

Product Overview

• Article Name: AR antagonist 17, CAS [[3064715-04-1]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-178148
• Supplier Catalog Number: HY-178148
• Alternative Catalog Number: MCE-HY-178148-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AR antagonist 17 is a selective, orally active, low brain-penetrant Androgen Receptor (AR) antagonist (IC50 = 0.010 µM), effectively blocking AR dimerization and nuclear translocation, and demonstrating potent efficacy in several castration-resistant prostate cancer (CRPC) cells. AR antagonist 17 showed superior efficacy against variant drug-resistant AR mutants. AR antagonist 17 can inhibit tumor growth in an LNCaP xenograft model without apparent toxicity. AR antagonist 17 can be used for the study of castration-resistant prostate cancer (CRPC)[1].

Product Properties

• Molecular Weight: 499.53
• CAS Number: [3064715-04-1]
• Formula: C21H20F3N3O4S2
• Target: Androgen Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound