PARP1-IN-46, CAS [[2505146-00-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: PARP1-IN-46, CAS [[2505146-00-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-178178
• Hersteller Artikelnummer: HY-178178
• Alternativnummer: MCE-HY-178178-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PARP1-IN-46 is a potent PARP-1 inhibitor with an IC50 of 2.4 nM. PARP1-IN-46 demonstrates remarkable anti-proliferative activity in both rat (C6) and human (U87MG) glioma cells. PARP1-IN-46 promotes PARP cleavage, triggers DNA damage, and increases ROS. PARP1-IN-46 effectively inhibits the migration, invasion and colony formation of glioma cells, and ultimately induces cell apoptosis. PARP1-IN-46 can be used to the study of glioma[1].

Produkteigenschaften

• Molekulargewicht: 305.28
• CAS Nummer: [2505146-00-7]
• Formel: C18H11NO4
• Target-Kategorie: Apoptosis,DNA/RNA Synthesis,PARP,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1