PARP1-IN-46, CAS [[2505146-00-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-178178
Supplier Catalog Number:
HY-178178
Alternative Catalog Number:
MCE-HY-178178-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PARP1-IN-46 is a potent PARP-1 inhibitor with an IC50 of 2.4 nM. PARP1-IN-46 demonstrates remarkable anti-proliferative activity in both rat (C6) and human (U87MG) glioma cells. PARP1-IN-46 promotes PARP cleavage, triggers DNA damage, and increases ROS. PARP1-IN-46 effectively inhibits the migration, invasion and colony formation of glioma cells, and ultimately induces cell apoptosis. PARP1-IN-46 can be used to the study of glioma[1].
Molecular Weight:
305.28
CAS Number:
[2505146-00-7]
Formula:
C18H11NO4
Target:
Apoptosis,DNA/RNA Synthesis,PARP,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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