alpha-Glucosidase-IN-98 is a potent orally active alpha-Glucosidase inhibitor with an IC50 of 18.1 µM. alpha-Glucosidase-IN-98 reversibly binds with alpha-Glucosidase via hydrogen bonds, electrostatic interactions and hydrophobic effects, which induces significant conformational alterations in the secondary structure of alpha-Glucosidase. alpha-Glucosidase-IN-98 decreases postprandial hyperglycemia in Starch (HY-B2225B)/Sucrose (HY-B1779)-challenged mice. alpha-Glucosidase-IN-98 can be used for type 2 diabetes mellitus (T2DM) research[1].
Molekulargewicht:
309.36
Formel:
C19H19NO3
Target-Kategorie:
Glycosidase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
