alpha-Glucosidase-IN-98 is a potent orally active alpha-Glucosidase inhibitor with an IC50 of 18.1 µM. alpha-Glucosidase-IN-98 reversibly binds with alpha-Glucosidase via hydrogen bonds, electrostatic interactions and hydrophobic effects, which induces significant conformational alterations in the secondary structure of alpha-Glucosidase. alpha-Glucosidase-IN-98 decreases postprandial hyperglycemia in Starch (HY-B2225B)/Sucrose (HY-B1779)-challenged mice. alpha-Glucosidase-IN-98 can be used for type 2 diabetes mellitus (T2DM) research[1].
Molecular Weight:
309.36
Formula:
C19H19NO3
Target:
Glycosidase
Application Notes:
MCE Product type: Reference compound
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