BChE/p38-alpha MAPK-IN-2 is a BChE and p38-alpha MAPK dual inhibitor. BChE/p38-alpha MAPK-IN-2 inhibits hBChE with an IC50 of 5.1 nM, showing 1000-fold selectivity over hAChE. BChE/p38-alpha MAPK-IN-2 inhibits p38alpha MAPK with an IC50 of 8.12 µM. BChE/p38-alpha MAPK-IN-2 exhibits neuroprotective effect and can be used for the research of neurological disease, such as Alzheimers disease[1].
Molekulargewicht:
491.58
Formel:
C27H33N5O4
Target-Kategorie:
Cholinesterase (ChE),p38 MAPK
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
