METTL3-IN-11, CAS [[3069369-05-4]] Preis auf Anfrage

Artikelnummer: MCE-HY-178446
Artikelname: METTL3-IN-11, CAS [[3069369-05-4]] Preis auf Anfrage
Artikelnummer: MCE-HY-178446
Hersteller Artikelnummer: HY-178446
Alternativnummer: MCE-HY-178446-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
METTL3-IN-11 is an excellent, selective METTL3 inhibitor (IC50 = 45.31 nM). METTL3-IN-11 exhibits high selectivity towards METTL3 compared to DNMT1, EZH1, MLL1, and PRMT1. METTL3-IN-11 reduces the m6A level of total RNA in MOLM-13 and SKOV3 cells, induces cell apoptosis, and inhibits cell migration. METTL3-IN-11 can reduce the expression of m6A downstream target genes (c-MYC and BCL2). METTL3-IN-11 can be used for the study of ovarian cancer and acute myeloid leukemia[1].
Molekulargewicht: 472.54
CAS Nummer: [3069369-05-4]
Formel: C26H28N6O3
Target-Kategorie: Bcl-2 Family,c-Myc,METTL3
Anwendungsbeschreibung: MCE Product type: Reference compound