METTL3-IN-11, CAS [[3069369-05-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-178446
Supplier Catalog Number:
HY-178446
Alternative Catalog Number:
MCE-HY-178446-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
METTL3-IN-11 is an excellent, selective METTL3 inhibitor (IC50 = 45.31 nM). METTL3-IN-11 exhibits high selectivity towards METTL3 compared to DNMT1, EZH1, MLL1, and PRMT1. METTL3-IN-11 reduces the m6A level of total RNA in MOLM-13 and SKOV3 cells, induces cell apoptosis, and inhibits cell migration. METTL3-IN-11 can reduce the expression of m6A downstream target genes (c-MYC and BCL2). METTL3-IN-11 can be used for the study of ovarian cancer and acute myeloid leukemia[1].
Molecular Weight:
472.54
CAS Number:
[3069369-05-4]
Formula:
C26H28N6O3
Target:
Bcl-2 Family,c-Myc,METTL3
Application Notes:
MCE Product type: Reference compound
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