RIPK1-IN-34, CAS [[3065634-19-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: RIPK1-IN-34, CAS [[3065634-19-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-178464
• Hersteller Artikelnummer: HY-178464
• Alternativnummer: MCE-HY-178464-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

RIPK1-IN-34 is a selective, brain-penetrant RIPK1 inhibitor (IC50 = 126.70 nM) with almost no inhibitory effect on RIPK3 (IC50 > 10, 000 nM). RIPK1-IN-34 offers substantial neuroprotection by inhibiting the phosphorylation of RIPK1, RIPK3, and mixed lineage kinase domain-like pseudokinase (MLKL) within the necroptosis pathway. RIPK1-IN-34 shows the neuroprotective effect in a rat middle cerebral artery occlusion (MCAO) model. RIPK1-IN-34 can be used for the study of anti-acute ischemic stroke (AIS)[1].

Produkteigenschaften

• Molekulargewicht: 491.54
• CAS Nummer: [3065634-19-4]
• Formel: C28H25N7O2
• Target-Kategorie: Mixed Lineage Kinase,Necroptosis,RIP kinase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound