FABP4/5-IN-6, CAS [[2975215-64-4]] Preis auf Anfrage
Artikelnummer:
MCE-HY-178471
Hersteller Artikelnummer:
HY-178471
Alternativnummer:
MCE-HY-178471-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
FABP4/5-IN-6 is an orally active, potent FABP4/5 inhibitor (Ki = 0.41/2.53 µM), showing low selectivity over FABP3 (Ki = 59.72 µM). FABP4/5-IN-6 inhibits the secretion of MCP-1 and IL-6 in Lipopolysaccharides (HY-D1056) (LPS)-induced THP-1 macrophage. FABP4/5-IN-6 exhibits significant anti-inflammatory effects and attenuates LPS-induced liver injury. FABP4/5-IN-6 has low hERG inhibition (LD50 > 2000 mg/kg). FABP4/5-IN-6 can be used for the study of Inflammation-related diseases[1].
Molekulargewicht:
420.26
CAS Nummer:
[2975215-64-4]
Formel:
C21H16Cl2FNO3
Target-Kategorie:
FABP,Interleukin Related
Anwendungsbeschreibung:
MCE Product type: Reference compound
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