FABP4/5-IN-6, CAS [[2975215-64-4]] Preis auf Anfrage

Product Overview

• Article Name: FABP4/5-IN-6, CAS [[2975215-64-4]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-178471
• Supplier Catalog Number: HY-178471
• Alternative Catalog Number: MCE-HY-178471-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

FABP4/5-IN-6 is an orally active, potent FABP4/5 inhibitor (Ki = 0.41/2.53 µM), showing low selectivity over FABP3 (Ki = 59.72 µM). FABP4/5-IN-6 inhibits the secretion of MCP-1 and IL-6 in Lipopolysaccharides (HY-D1056) (LPS)-induced THP-1 macrophage. FABP4/5-IN-6 exhibits significant anti-inflammatory effects and attenuates LPS-induced liver injury. FABP4/5-IN-6 has low hERG inhibition (LD50 > 2000 mg/kg). FABP4/5-IN-6 can be used for the study of Inflammation-related diseases[1].

Product Properties

• Molecular Weight: 420.26
• CAS Number: [2975215-64-4]
• Formula: C21H16Cl2FNO3
• Target: FABP,Interleukin Related

Application Notes

• Application Notes: MCE Product type: Reference compound1