AMG-315 is a selective and potent CB1 agonist with a Ki of 7.8 nM and an EC50 of 0.6 nM. AMG-315 can significantly inhibit the cAMP production induced by Forskolin (HY-15371) with the maximum inhibitory effect reaching 76%. AMG-315 has significant stability against all endogenous cannabinoid hydrolases and oxidases. AMG-315 increases the mechanical withdrawal threshold in CFA (HY-153808)-induced inflammatory pain model. AMG-315 can be used for the research of inflammation[1].
Molekulargewicht:
375.59
CAS Nummer:
[2244425-65-6]
Formel:
C24H41NO2
Target-Kategorie:
Cannabinoid Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
