SIRT2-IN-18, CAS [[858032-59-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: SIRT2-IN-18, CAS [[858032-59-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-178773
• Hersteller Artikelnummer: HY-178773
• Alternativnummer: MCE-HY-178773-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

SIRT2-IN-18 (Compound 8) is a SIRT2 inhibitor with IC50s of 5.3 and 12.3 µM for SmSIRT2 and hSIRT2, respectively. SIRT2-IN-18 shows potent antischistosomal activities against both Liberian and Puerto Rican strains of Schistosoma mansoni and reduces schistosomula and adult worm pair viability, pairing, and egg production, with low cytotoxicity in mammalian cells. SIRT2-IN-18 increases histone H3 hyperacetylation and induces cytochrome c-mediated apoptosis[1].

Produkteigenschaften

• Molekulargewicht: 340.33
• CAS Nummer: [858032-59-4]
• Formel: C21H12N2O3
• Target-Kategorie: Apoptosis,Sirtuin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound