SIRT2-IN-18, CAS [[858032-59-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-178773
Supplier Catalog Number:
HY-178773
Alternative Catalog Number:
MCE-HY-178773-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
SIRT2-IN-18 (Compound 8) is a SIRT2 inhibitor with IC50s of 5.3 and 12.3 µM for SmSIRT2 and hSIRT2, respectively. SIRT2-IN-18 shows potent antischistosomal activities against both Liberian and Puerto Rican strains of Schistosoma mansoni and reduces schistosomula and adult worm pair viability, pairing, and egg production, with low cytotoxicity in mammalian cells. SIRT2-IN-18 increases histone H3 hyperacetylation and induces cytochrome c-mediated apoptosis[1].
Molecular Weight:
340.33
CAS Number:
[858032-59-4]
Formula:
C21H12N2O3
Target:
Apoptosis,Sirtuin
Application Notes:
MCE Product type: Reference compound
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