Tyk2-IN-23, CAS [[2734918-75-1]] Preis auf Anfrage

Artikelnummer: MCE-HY-178913
Artikelname: Tyk2-IN-23, CAS [[2734918-75-1]] Preis auf Anfrage
Artikelnummer: MCE-HY-178913
Hersteller Artikelnummer: HY-178913
Alternativnummer: MCE-HY-178913-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Tyk2-IN-23 is a potent, orally active, selective TYK2 inhibitor (IC50 = 18 nM), exhibiting more than > 70-fold selectivity over JAK1/2/3 isoforms. Tyk2-IN-23 potently inhibits p-STAT3 in TYK2-dependent signaling activated by IFN-alpha and IL-10. Tyk2-IN-23 potently inhibits IFN-alpha-induced STAT1 phosphorylation in H9 cells. Tyk2-IN-23 can be used for the study of alopecia areata and allergic Rhinitis[1].
Molekulargewicht: 495.98
CAS Nummer: [2734918-75-1]
Formel: C26H27ClFN5O2
Target-Kategorie: JAK,STAT
Anwendungsbeschreibung: MCE Product type: Reference compound