Tyk2-IN-23, CAS [[2734918-75-1]] Preis auf Anfrage

Product Overview

• Article Name: Tyk2-IN-23, CAS [[2734918-75-1]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-178913
• Supplier Catalog Number: HY-178913
• Alternative Catalog Number: MCE-HY-178913-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Tyk2-IN-23 is a potent, orally active, selective TYK2 inhibitor (IC50 = 18 nM), exhibiting more than > 70-fold selectivity over JAK1/2/3 isoforms. Tyk2-IN-23 potently inhibits p-STAT3 in TYK2-dependent signaling activated by IFN-alpha and IL-10. Tyk2-IN-23 potently inhibits IFN-alpha-induced STAT1 phosphorylation in H9 cells. Tyk2-IN-23 can be used for the study of alopecia areata and allergic Rhinitis[1].

Product Properties

• Molecular Weight: 495.98
• CAS Number: [2734918-75-1]
• Formula: C26H27ClFN5O2
• Target: JAK,STAT

Application Notes

• Application Notes: MCE Product type: Reference compound