PROTAC GPX4 degrader-5 is an efficient and highly selective GPX4 PROTAC degrader (DC50 = 28 nM). PROTAC GPX4 degrader-5 can induce ferroptosis and has low toxicity to normal cells. PROTAC GPX4 degrader-5 can significantly increase ROS. PROTAC GPX4 degrader-5 exerts anti proliferative effects on various tumor cells. PROTAC GPX4 degrader-5 is commonly used in cancer research. (Pink: GPX4 Ligand (HY-179294), Blue: Hyt Hydrophobic group (HY-N2427), Black: Linker (HY-W047688))[1]
Molekulargewicht:
827.51
Formel:
C47H59ClN4O5S
Target-Kategorie:
Ferroptosis,Glutathione Peroxidase,PROTACs,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
