STING-IN-17, CAS [[3069635-58-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: STING-IN-17, CAS [[3069635-58-8]] Preis auf Anfrage
• Artikelnummer: MCE-HY-178951
• Hersteller Artikelnummer: HY-178951
• Alternativnummer: MCE-HY-178951-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

STING-IN-17 is an orally active STING (human STING IC50 = 29 nM, mouse STING IC50 = 15 nM) inhibitor. STING-IN-17 can inhibit the phosphorylation of STING, TBK1 and IRF3. STING-IN-17 dose dependently inhibits the mRNA expression of IP10, IFNB1 and ISG56. STING-IN-17 can reduce ROS and inhibit the expression of cleaved-PARP/caspase-3. STING-IN-17 can improve kidney function. STING-IN-17 can be used for research on inflammatory conditions such as acute kidney injury[1].

Produkteigenschaften

• Molekulargewicht: 550.55
• CAS Nummer: [3069635-58-8]
• Formel: C30H26F4N4O2
• Target-Kategorie: Caspase,IFNAR,IKK,PARP,Reactive Oxygen Species (ROS),STING

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound