STING-IN-17, CAS [[3069635-58-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-178951
Supplier Catalog Number:
HY-178951
Alternative Catalog Number:
MCE-HY-178951-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
STING-IN-17 is an orally active STING (human STING IC50 = 29 nM, mouse STING IC50 = 15 nM) inhibitor. STING-IN-17 can inhibit the phosphorylation of STING, TBK1 and IRF3. STING-IN-17 dose dependently inhibits the mRNA expression of IP10, IFNB1 and ISG56. STING-IN-17 can reduce ROS and inhibit the expression of cleaved-PARP/caspase-3. STING-IN-17 can improve kidney function. STING-IN-17 can be used for research on inflammatory conditions such as acute kidney injury[1].
Molecular Weight:
550.55
CAS Number:
[3069635-58-8]
Formula:
C30H26F4N4O2
Target:
Caspase,IFNAR,IKK,PARP,Reactive Oxygen Species (ROS),STING
Application Notes:
MCE Product type: Reference compound
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