PROTAC DAPK1 Degrader-1, CAS [[3063030-38-3]]

Produktübersicht

• Artikelname: PROTAC DAPK1 Degrader-1, CAS [[3063030-38-3]]
• Artikelnummer: MCE-HY-179055
• Hersteller Artikelnummer: HY-179055
• Alternativnummer: MCE-HY-179055-1MG, MCE-HY-179055-5MG, MCE-HY-179055-10MG, MCE-HY-179055-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC DAPK1 Degrader-1 (Compound CP1) is a DAPK1 PROTAC degrader with a DC50 of 119.6 nM. PROTAC DAPK1 Degrader-1 significantly increased the MDM2 protein level. PROTAC DAPK1 Degrader-1 significantly reduced the levels of cleaved caspase-3 and cleaved PARP in a cell apoptosis model induced by the neurotoxin ceramide, indicating that it effectively inhibits neuronal apoptosis by degrading DAPK1. PROTAC DAPK1 Degrader-1 can be used to study neurological diseases such as cerebral ischemia and traumatic brain injury (pink: DAPK1 ligand (HY-179071), blue: CRBN ligand (HY-10984), black: linker (HY-40171))[1].

Produkteigenschaften

• Molekulargewicht: 657.66
• Reinheit: 93.24
• CAS Nummer: [3063030-38-3]
• Formel: C30H27N9O7S
• Target-Kategorie: DAPK,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound