PLK4-IN-5 (compound 5f) is a PLK4 (IC50 = 0.8 nM) inhibitor. PLK4-IN-5 can inhibit MCF-7 cell clone formation, induce cell cycle arrest (S/G2 phase), and apoptosis. PLK4-IN-5 has anti proliferative activity against MCF-7 cells (IC50 = 0.48 µM). PLK4-IN-5 can be used in the research of cancer such as breast cancer[1].
Molekulargewicht:
476.01
Formel:
C21H22ClN5O2S2
Target-Kategorie:
Apoptosis,Polo-like Kinase (PLK)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
