CDK2-IN-49 (Compound 5j) is a CDK2 inhibitor with an IC50 of 0.25 µM. CDK2-IN-49 shows potent activity against CDK7 with an IC50 of 0.14 µM. CDK2-IN-49 induces Apoptosis by raising the levels of p53 and Bax protein expression while reducing the amount of Bcl-2. CDK2-IN-49 inhibits cell division. CDK2-IN-49 can be used in the research of cancer[1].
Molekulargewicht:
358.40
Formel:
C20H18N6O
Target-Kategorie:
Apoptosis,Bcl-2 Family,CDK,MDM-2/p53
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
