3-Oxochol-5-en-24-oic acid, CAS [[847232-54-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: 3-Oxochol-5-en-24-oic acid, CAS [[847232-54-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-179476
• Hersteller Artikelnummer: HY-179476
• Alternativnummer: MCE-HY-179476-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

3-Oxochol-5-en-24-oic acid is a rare bile acid produced by the intestinal microbiota. 3-Oxochol-5-en-24-oic acid is a potent antagonist of the human androgen receptor (hAR), with an IC50 of 119.4 nM. 3-Oxochol-5-en-24-oic acid has no significant agonistic or antagonistic effects on estrogen receptors (ER) or glucocorticoid receptors (GR). 3-Oxochol-5-en-24-oic acid effectively inhibits the growth of prostate cancer cells. In animal models, it enhances the efficacy of anti-PD-1 therapy by regulating the differentiation of CD8+ T cells. 3-Oxochol-5-en-24-oic acid can be used for research on regulating host immunity and anti-tumor studies[1].

Produkteigenschaften

• Molekulargewicht: 372.54
• CAS Nummer: [847232-54-6]
• Formel: C24H36O3
• Target-Kategorie: Androgen Receptor,Endogenous Metabolite

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products