PROTAC EZH2 Degrader-9, CAS [[2978620-84-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC EZH2 Degrader-9, CAS [[2978620-84-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-179499
• Hersteller Artikelnummer: HY-179499
• Alternativnummer: MCE-HY-179499-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC EZH2 Degrader-9 is orally active EZH2 PROTAC degrader degrading EZH2 via the ubiquitin-proteasome pathway. PROTAC EZH2 Degrader-9 downregulates PRC2 core subunits and potent inhibition of H3K27me3 without affecting common CRBN neosubstrates while it was selective over GSpT1 and ikZF1/3. PROTAC EZH2 Degrader-9 exhibits potent antiproliferative activity against multiple cancer cell lines by inducing cell cycle and apoptosis. PROTAC EZH2 Degrader-9 reverses PRC2-mediated gene silencing and inhibiting EZH2 non-catalytic target gene activation. PROTAC EZH2 Degrader-9 can be used for leukemia, lymphoma, and non-small cell lung cancer research[1].

Produkteigenschaften

• Molekulargewicht: 882.06
• CAS Nummer: [2978620-84-5]
• Formel: C51H59N7O7
• Target-Kategorie: Apoptosis,Histone Methyltransferase,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound