PROTAC EZH2 Degrader-9, CAS [[2978620-84-5]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC EZH2 Degrader-9, CAS [[2978620-84-5]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-179499
• Supplier Catalog Number: HY-179499
• Alternative Catalog Number: MCE-HY-179499-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC EZH2 Degrader-9 is orally active EZH2 PROTAC degrader degrading EZH2 via the ubiquitin-proteasome pathway. PROTAC EZH2 Degrader-9 downregulates PRC2 core subunits and potent inhibition of H3K27me3 without affecting common CRBN neosubstrates while it was selective over GSpT1 and ikZF1/3. PROTAC EZH2 Degrader-9 exhibits potent antiproliferative activity against multiple cancer cell lines by inducing cell cycle and apoptosis. PROTAC EZH2 Degrader-9 reverses PRC2-mediated gene silencing and inhibiting EZH2 non-catalytic target gene activation. PROTAC EZH2 Degrader-9 can be used for leukemia, lymphoma, and non-small cell lung cancer research[1].

Product Properties

• Molecular Weight: 882.06
• CAS Number: [2978620-84-5]
• Formula: C51H59N7O7
• Target: Apoptosis,Histone Methyltransferase,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound