AChE/BChE-IN-32 (Compound 4a) is an AChE and BChE inhibitor, with Ki values of 2.48 and 0.696 µM respectively. AChE/BChE-IN-32 inhibits Abeta aggregation and exhibits a strong ABTS+ scavenging ability (TEAC = 2.40). AChE/BChE-IN-32 shows significant neuroprotective activity in glutamate and hydrogen peroxide-induced oxidative stress models. AChE/BChE-IN-32 can be used for the study of Alzheimers disease[1].
Molekulargewicht:
410.55
Formel:
C24H34N4O2
Target-Kategorie:
Amyloid-beta,Cholinesterase (ChE)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
