AChE/BChE-IN-32 (Compound 4a) is an AChE and BChE inhibitor, with Ki values of 2.48 and 0.696 µM respectively. AChE/BChE-IN-32 inhibits Abeta aggregation and exhibits a strong ABTS+ scavenging ability (TEAC = 2.40). AChE/BChE-IN-32 shows significant neuroprotective activity in glutamate and hydrogen peroxide-induced oxidative stress models. AChE/BChE-IN-32 can be used for the study of Alzheimers disease[1].
Molecular Weight:
410.55
Formula:
C24H34N4O2
Target:
Amyloid-beta,Cholinesterase (ChE)
Application Notes:
MCE Product type: Reference compound
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