Photosensitizer-8, CAS [[3106369-28-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: Photosensitizer-8, CAS [[3106369-28-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-180169
• Hersteller Artikelnummer: HY-180169
• Alternativnummer: MCE-HY-180169-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Photosensitizer-8 (Compound 4), 2-anthrol derivative, is an alkaline phosphatase (ALP)-activatable photosensitizer. Photosensitizer-8 undergoes a phosphate ester hydrolysis reaction in the presence of ALP, rapidly converting into the active photosensitizer 2-anthrol. Photosensitizer-8 exhibits cytotoxicity against ALP-overexpressing cancer cells (HeLa, A549, HCT116) after light exposure, with IC50 values of 14.3 µM, 21.6 µM and 17.5 µM, respectively, while showing no significant cytotoxicity against normal lung fibroblasts (WI-38) (IC50 30 µM). Photosensitizer-8 can be used in photodynamic therapy research for ALP-overexpression-related cancers[1].

Produkteigenschaften

• Molekulargewicht: 274.21
• CAS Nummer: [3106369-28-9]
• Formel: C14H11O4P
• Target-Kategorie: Drug Derivative,Photosensitizer

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound