Photosensitizer-8, CAS [[3106369-28-9]] Preis auf Anfrage

Product Overview

• Article Name: Photosensitizer-8, CAS [[3106369-28-9]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-180169
• Supplier Catalog Number: HY-180169
• Alternative Catalog Number: MCE-HY-180169-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Photosensitizer-8 (Compound 4), 2-anthrol derivative, is an alkaline phosphatase (ALP)-activatable photosensitizer. Photosensitizer-8 undergoes a phosphate ester hydrolysis reaction in the presence of ALP, rapidly converting into the active photosensitizer 2-anthrol. Photosensitizer-8 exhibits cytotoxicity against ALP-overexpressing cancer cells (HeLa, A549, HCT116) after light exposure, with IC50 values of 14.3 µM, 21.6 µM and 17.5 µM, respectively, while showing no significant cytotoxicity against normal lung fibroblasts (WI-38) (IC50 30 µM). Photosensitizer-8 can be used in photodynamic therapy research for ALP-overexpression-related cancers[1].

Product Properties

• Molecular Weight: 274.21
• CAS Number: [3106369-28-9]
• Formula: C14H11O4P
• Target: Drug Derivative,Photosensitizer

Application Notes

• Application Notes: MCE Product type: Reference compound