HDAC6-IN-69 is a brain-penetrant and highly selective HDAC6 inhibitor with an IC50 of 4.0 nM. HDAC6-IN-69 shows >176-fold against other HDAC isoforms. HDAC6-IN-69 engages the target in neuronal cells by dose-dependently upregulating acetylated alpha-tubulin in virto. HDAC6-IN-69 has neuroprotective effect and can be used for ischemic stroke research [1].
Molekulargewicht:
425.30
Formel:
C17H17BrN2O4S
Target-Kategorie:
HDAC
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
