HDAC6-IN-69 is a brain-penetrant and highly selective HDAC6 inhibitor with an IC50 of 4.0 nM. HDAC6-IN-69 shows >176-fold against other HDAC isoforms. HDAC6-IN-69 engages the target in neuronal cells by dose-dependently upregulating acetylated alpha-tubulin in virto. HDAC6-IN-69 has neuroprotective effect and can be used for ischemic stroke research [1].
Molecular Weight:
425.30
Formula:
C17H17BrN2O4S
Target:
HDAC
Application Notes:
MCE Product type: Reference compound
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